[url]http://www.nytimes.com/2014/05/25/magaz ... ticle&_r=0[/url]
Ook in NL worden enkele patiënten met RA op deze manier behandeld!
Dysautonomie
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joge
TVAM zo noemt Arrata zijn behandeling, is veilig. Zegt Arrata. ;)
Maar goed, uit alle ccsvi onderzoek blijkt dat gelukkig ook!
[url]http://www.minervamedica.it/en/journals ... 14N01A0019[/url]
Maar goed, uit alle ccsvi onderzoek blijkt dat gelukkig ook!
[url]http://www.minervamedica.it/en/journals ... 14N01A0019[/url]
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Robbie
[url]http://jevt.org/doi/full/10.1583/13-4605MR.1[/url]
[QUOTE]Purpose: To describe the use of transvascular autonomic modulation (TVAM) to improve cardiovascular autonomic nervous system (ANS) dysfunction in multiple sclerosis (MS) patients, comparing the safety and efficacy of this modified technique with traditional balloon angioplasty.
Methods: Twenty-one MS patients (11 men; mean age 48.7±13.0 years) who presented with symptoms of cardiovascular ANS dysfunction underwent TVAM. These patients were compared with age/sex-matched MS patients (10 men; 49.3±11.1 years) in the same stages of the disease who presented with chronic cerebrospinal venous insufficiency (CCSVI) and who underwent venous balloon angioplasty. TVAM involved the coupling of balloon angioplasty of the internal jugular veins with the application of external manual compression and dilation of the azygos and renal veins; unlike traditional angioplasty for CCSVI, which treats only abnormal veins (≥50% stenosis or static valve), all targeted vessels were treated with TVAM regardless of the presence of an abnormality. The effect of TVAM on ANS function was indicated by determining heart rate variability based on the electrocardiographic R-R interval lengths using vector analysis to derive the mean circular resultant (MCR) and the expiration/inspiration (E/I) ratio, the Valsalva ratio, and the 30:15 postural ratio at 24 hours after intervention.
Results: Left renal vein compression was common among the TVAM patients and resulted in ≥50% luminal compromise in 10 of 21 patients. Azygos vein abnormalities (a static valve) were identified in 5 patients. Overall, 18 patients met the diagnostic criteria for CCSVI with at least one lesion >50%, but only 10 lesions were considered treatable by traditional balloon angioplasty. After intervention, the R-R interval values, including the 30:15 postural ratio (p=0.01), the MCR (p=0.1), and E/I ratio (p=0.1), were higher for the TVAM patients compared to the control group. The safety profile of the TVAM procedure was similar to that of traditional balloon angioplasty.
Conclusion: The combination of balloon angioplasty of anatomically normal veins coupled with external compression during dilation of these veins can improve indicators of ANS dysfunction. The safety and efficacy of TVAM in MS patients observed in this pilot study is encouraging, paving the way for the treatment of dysautonomia in pathological states other than MS. Further studies should investigate TVAM in a larger MS cohort.
. [/QUOTE]
[QUOTE]Purpose: To describe the use of transvascular autonomic modulation (TVAM) to improve cardiovascular autonomic nervous system (ANS) dysfunction in multiple sclerosis (MS) patients, comparing the safety and efficacy of this modified technique with traditional balloon angioplasty.
Methods: Twenty-one MS patients (11 men; mean age 48.7±13.0 years) who presented with symptoms of cardiovascular ANS dysfunction underwent TVAM. These patients were compared with age/sex-matched MS patients (10 men; 49.3±11.1 years) in the same stages of the disease who presented with chronic cerebrospinal venous insufficiency (CCSVI) and who underwent venous balloon angioplasty. TVAM involved the coupling of balloon angioplasty of the internal jugular veins with the application of external manual compression and dilation of the azygos and renal veins; unlike traditional angioplasty for CCSVI, which treats only abnormal veins (≥50% stenosis or static valve), all targeted vessels were treated with TVAM regardless of the presence of an abnormality. The effect of TVAM on ANS function was indicated by determining heart rate variability based on the electrocardiographic R-R interval lengths using vector analysis to derive the mean circular resultant (MCR) and the expiration/inspiration (E/I) ratio, the Valsalva ratio, and the 30:15 postural ratio at 24 hours after intervention.
Results: Left renal vein compression was common among the TVAM patients and resulted in ≥50% luminal compromise in 10 of 21 patients. Azygos vein abnormalities (a static valve) were identified in 5 patients. Overall, 18 patients met the diagnostic criteria for CCSVI with at least one lesion >50%, but only 10 lesions were considered treatable by traditional balloon angioplasty. After intervention, the R-R interval values, including the 30:15 postural ratio (p=0.01), the MCR (p=0.1), and E/I ratio (p=0.1), were higher for the TVAM patients compared to the control group. The safety profile of the TVAM procedure was similar to that of traditional balloon angioplasty.
Conclusion: The combination of balloon angioplasty of anatomically normal veins coupled with external compression during dilation of these veins can improve indicators of ANS dysfunction. The safety and efficacy of TVAM in MS patients observed in this pilot study is encouraging, paving the way for the treatment of dysautonomia in pathological states other than MS. Further studies should investigate TVAM in a larger MS cohort.
. [/QUOTE]
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joge
[url]http://ki.se/en/news/unexpected-origin- ... ous-system[/url]
Interessant verhaal over het autonome zenuwstelsel!
Interessant verhaal over het autonome zenuwstelsel!
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joge
Met dank aan Robbie: Zamboni over het prikkelen van de Nervus Vagus.
[url]http://www.pagepressjournals.org/index. ... .4526/4004[/url]
Zamboni over dysautonomie en tvam:
The Authors are providing very interesting data about additional effects of venous PTA linked with vagus stimulation in consequence of balloon inflation. My second consideration is that these further therapeutic effects may contribute to explain us the rapid recovery of autonomic symptoms referred by the vast majority of patients after balloon angioplasty, usually considered placebo effect.
[url]http://www.pagepressjournals.org/index. ... .4526/4004[/url]
Zamboni over dysautonomie en tvam:
The Authors are providing very interesting data about additional effects of venous PTA linked with vagus stimulation in consequence of balloon inflation. My second consideration is that these further therapeutic effects may contribute to explain us the rapid recovery of autonomic symptoms referred by the vast majority of patients after balloon angioplasty, usually considered placebo effect.
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joge
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Robbie
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joge
En ook hier weer de Nervus Vagus als "sleutel".
[url]http://news.sciencemag.org/biology/2014 ... ma-attacks[/url]
[url]http://news.sciencemag.org/biology/2014 ... ma-attacks[/url]