MS en de relatie met de darmen
Geplaatst: 01 nov 2011, 01:03
Het volgende artikel is al eerder in een ander topic verschenen, maar voor de overzichtelijkheid plaats ik het in een nieuw topic.
Natural Intestinal Flora Involved in the Emergence of Multiple Sclerosis, [URL="http://www.sciencedaily.com/releases/20 ... 112520.htm"][U]Study[/U][/URL] Finds
[QUOTE]Multiple sclerosis is caused by a combination of genetic and environmental factors. For a long time, pathogens were believed to be such external influences.
According to scientists from the Max Planck Institute of Neurobiology in Martinsried, however, it is apparently [B]not harmful bacteria[/B] that trigger multiple sclerosis, but [B]beneficial ones -- specifically, the natural intestinal flora[/B], which every human being needs for digestion.[/QUOTE]
[QUOTE]"It appears that the immune system is activated in two stages: to begin, the T cells in the lymph vessels of the intestinal tract become active and proliferate. Together with the surface proteins of the myelin layer, these then stimulate the B cells to form pathogenic antibodies. Both processes trigger inflammatory reactions in the brain which progressively destroy the myelin layer -- a process that is very similar to the way multiple sclerosis develops in humans," says Gurumoorthy Krishnamoorthy from the Max Planck Institute of Neurobiology. Thus, the disease is caused by changes in the immune system and not by disturbances in the functioning of the nervous system.[/QUOTE]
[QUOTE]The scientists are certain that the intestinal flora can also trigger an overreaction of the immune system against the myelin layer in persons with a genetic predisposition for multiple sclerosis. Therefore, nutrition may play a central role in the disease, as diet largely determines the bacteria that colonise the intestines. "Changing eating habits could explain, for example, why the incidence of multiple sclerosis has increased in Asian countries in recent years," explains Hartmut Wekerle.
Precisely which bacteria are involved in the emergence of multiple sclerosis remains unclear. Possible candidates are clostridiums, which can have direct contact with the intestinal wall.
[/QUOTE]
[QUOTE]The scientists would now like to analyse the entire microbial genome of patients with multiple sclerosis and thereby identify the differences in the intestinal flora of healthy people and multiple sclerosis patients.[/QUOTE]
Natural Intestinal Flora Involved in the Emergence of Multiple Sclerosis, [URL="http://www.sciencedaily.com/releases/20 ... 112520.htm"][U]Study[/U][/URL] Finds
[QUOTE]Multiple sclerosis is caused by a combination of genetic and environmental factors. For a long time, pathogens were believed to be such external influences.
According to scientists from the Max Planck Institute of Neurobiology in Martinsried, however, it is apparently [B]not harmful bacteria[/B] that trigger multiple sclerosis, but [B]beneficial ones -- specifically, the natural intestinal flora[/B], which every human being needs for digestion.[/QUOTE]
[QUOTE]"It appears that the immune system is activated in two stages: to begin, the T cells in the lymph vessels of the intestinal tract become active and proliferate. Together with the surface proteins of the myelin layer, these then stimulate the B cells to form pathogenic antibodies. Both processes trigger inflammatory reactions in the brain which progressively destroy the myelin layer -- a process that is very similar to the way multiple sclerosis develops in humans," says Gurumoorthy Krishnamoorthy from the Max Planck Institute of Neurobiology. Thus, the disease is caused by changes in the immune system and not by disturbances in the functioning of the nervous system.[/QUOTE]
[QUOTE]The scientists are certain that the intestinal flora can also trigger an overreaction of the immune system against the myelin layer in persons with a genetic predisposition for multiple sclerosis. Therefore, nutrition may play a central role in the disease, as diet largely determines the bacteria that colonise the intestines. "Changing eating habits could explain, for example, why the incidence of multiple sclerosis has increased in Asian countries in recent years," explains Hartmut Wekerle.
Precisely which bacteria are involved in the emergence of multiple sclerosis remains unclear. Possible candidates are clostridiums, which can have direct contact with the intestinal wall.
[/QUOTE]
[QUOTE]The scientists would now like to analyse the entire microbial genome of patients with multiple sclerosis and thereby identify the differences in the intestinal flora of healthy people and multiple sclerosis patients.[/QUOTE]