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Voeding en supplementen

Alles omtrent voeding en supplementen
RoOsJe *59

Bericht door RoOsJe *59 »

En weer heel hartelijk bedankt Marc.:hand:
Marsei

Can diet help reduce disability, symptoms of MS?

Bericht door Marsei »

Can diet help reduce disability, symptoms of MS?

Van Ashton Embry:
[QUOTE][INDENT]Diet and disability symptoms of MS - A [URL="https://www.eurekalert.org/pub_releases ... 113017.php"][U]paper[/U][/URL] has just been released in the journal Neurology which looks at the association of various diets and disabilities of persons with MS. It was found that people with an overall healthy lifestyle were nearly 50 percent less likely to have depression, 30 percent less likely to have severe fatigue and more than 40 percent less likely to have pain than people who did not have a healthy lifestyle. [/INDENT][/QUOTE]

Can diet help reduce disability, symptoms of MS?:
[QUOTE]For people with multiple sclerosis (MS), eating a healthy diet of fruits, vegetables and whole grains may be linked to having less disability and fewer symptoms than people whose diet is less healthy, according to a study published in the December 6, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.[/QUOTE]
[QUOTE]The study involved 6,989 people with all types of MS who completed questionnaires about their diet as part of the North American Research Committee (NARCOMS) registry. The definition of a healthy diet focused on eating more fruits, vegetables, legumes and whole grains and less sugar from desserts and sweetened beverages and less red meat and processed meat. The participants were divided into five groups based on how healthy their diet was.

Researchers also assessed whether participants had an overall healthy lifestyle, which was defined as having a healthy weight, getting regular physical activity, eating a better than average diet and not smoking.

The participants were also asked whether they had a relapse of MS symptoms or a gradual worsening of symptoms in the past six months and reported their level of disability and how severe their symptoms were in areas such as fatigue, mobility, pain and depression.

People in the group with the healthiest diet were 20 percent less likely to have more severe physical disability than people in the group with the least healthy diet. The results were true even after researchers adjusted for other factors that could affect disability, such as age and how long they had MS. Individuals with the healthiest diets also were also around 20 percent less likely to have more severe depression than individuals with the least healthy diet.

Those with the best diet ate an average of 1.7 servings of whole grains per day, compared to 0.3 servings per day for those with the least healthy diet. For fruits, vegetables, and legumes (not including French fries), the top group had 3.3 servings per day while the bottom group had 1.7 servings per day.

People with an overall healthy lifestyle were nearly 50 percent less likely to have depression, 30 percent less likely to have severe fatigue and more than 40 percent less likely to have pain than people who did not have a healthy lifestyle.

The study also looked at whether people followed a specific diet, including popular diets such as Paleo, weight-loss plans or diets that have been touted in self-help books and websites as beneficial for people with MS, such as the Wahls' diet. The researchers found that overall, past or current use of these diets was associated with modestly reduced risk of increased disability.

Fitzgerald said one limitation of the study is that due to study design, it cannot be known if healthy diets predict changes to MS symptoms in the future. Another limitation was that the participants mostly tended to be older, mainly white and had been diagnosed with MS for an average of nearly 20 years, so the results may not be applicable to everyone with MS.[/QUOTE]
Team Life Hack

"Voeding verbetert gezondheid bij MS"

Bericht door Team Life Hack »

"Voeding verbetert gezondheid bij MS"

Resultaat van recent Nederlands onderzoek:
[URL="http://www.nieuwsvoordietisten.nl/nieuw ... -en-reuma/"]Verse, onbewerkte voeding verbetert gezondheid bij MS en reuma[/URL]
Sara

Bericht door Sara »

Er nemen mensen deel op een moment dat ze gemotiveerd zijn om te iets aan hun leefstijl te gaan doen. Best kans dat ze ook meer zijn gaan sporten in die tijd, en dat de verbetering daardoor komt.

Daarnaast is er geen controlegroep die evenveel ondersteuning kreeg, maar zonder voedingsadvies. Is ook moeilijk natuurlijk met dit soort onderzoek, dat snap ik wel.

Idealiter is een onderzoek placebo-gecontroleerd, gerandomiseerd (het lot wijst aan wie meedoet en wie een placebo krijgt of niks) en geblindeerd.

Snappable dat dat niet lukt, maar de conclusie mag wél iets voorzichtiger wat mij betreft.

Groep enthousiaste mensen met MS voelt zich beter na begeleide verandering van voedingspatroon.

Zoiets!

Datzelfde zou trouwens waarschijnlijk ook voor gezonde mensen en mensen met een andere ziekte dan MS of reuma gelden :)
Marsei

New research on cholesterol clearance and MS

Bericht door Marsei »

New research on cholesterol clearance and MS

Blog Joan: New research on [URL="http://ccsviinms.blogspot.nl/2018/01/ne ... onnection)"][U]cholesterol clearance[/U][/URL] and MS
[QUOTE]
Research published this week from the Technical University of Munich explores how the degredation of myelin leaves a destructive cholesterol residue in the brain, which increases an inflammatory response and blocks myelin regeneration. It appears that with age, the process of transporting cholesterol out of the brain becomes less efficient. (Important to state that this research was done on a mouse model of MS.)

"Myelin contains a very high amount of cholesterol," explains Prof. Simons. "When myelin is destroyed, the cholesterol released has to be removed from the tissue." This is performed by microglia and macrophages, also referred to as phagocytes. They take up the damaged myelin, digest it and transport the non-digestible remainder, such as cholesterol, out of the cell by transport molecules. However, if too much cholesterol accumulates in the cell, cholesterol can forms needle-shaped crystals, which cause damage the cell. Using a mouse model, Simons and his team showed the devastating impact of the crystalline cholesterol: It activates the so-called inflammasome in phagocytes, which results in the release of inflammatory mediators, attracting even more immune cells. "Very similar problems occur in arteriosclerosis, however not in the brain tissue, but in blood vessels," says Simons.

Although cholesterol synthesis in the brain is considered a different process than cholesterol synthesis in the rest of the body, lower plasma levels of HDL cholesterol have been found to be related to MS. Cardiovascular researchers have been looking at this fact, in relation to the heart brain connection.

HDL plasma levels have also been associated with other neurodegenerative diseases such as multiple sclerosis (MS).74 Patients in the acute phase MS have been reported to have lower HDL-C levels compared with those in the remission phase, and they show a higher probability of developing acute inflammatory lesions (assessed by MRI).74–768 Moreover, HDL inhibits cytokine-induced expression of adhesion molecules in endothelial cells.72
link

Why are HDL levels important? Because HDL, also known as "good cholesterol", contains the transport protein ApoA1---needed to take cholesterol out of the blood and tissue.

Here's more research on low levels of ApoA1 found to be linked to MS severity. The lower HDL
ApoA1 plasma levels, the more severe the disease.

ApoA1 was reduced by approximately 25% in patients with relapsing-remitting MS, 50% in those with secondary progressive MS, and 75% in patients with primary progressive MS, the most severe form of the disease.[/QUOTE]
Marsei

Diet quality is associated with disability and symptom severity in multiple sclerosis

Bericht door Marsei »

Diet quality is associated with disability and symptom severity in multiple sclerosis

[URL="http://n.neurology.org/content/early/20 ... 0000004768"][U]Diet quality[/U][/URL] is associated with disability and symptom severity in multiple sclerosis

[QUOTE][B]Abstract[/B]

[B]Objective[/B] To assess the association between diet quality and intake of specific foods with disability and symptom severity in people with multiple sclerosis (MS).

[B]Methods[/B] In 2015, participants in the North American Research Committee on MS (NARCOMS) Registry completed a dietary screener questionnaire that estimates intake of fruits, vegetables and legumes, whole grains, added sugars, and red/processed meats. We constructed an overall diet quality score for each individual based on these food groups; higher scores denoted a healthier diet. We assessed the association between diet quality and disability status as measured using Patient-Determined Disease Steps (PDDS) and symptom severity using proportional odds models, adjusting for age, sex, income, body mass index, smoking status, and disease duration. We assessed whether a composite healthy lifestyle measure, a healthier diet, healthy weight (body mass index <25), routine physical activity, and abstinence from smoking was associated with symptom severity.
[B]
Results[/B] Of the 7,639 (68%) responders, 6,989 reported physician-diagnosed MS and provided dietary information. Participants with diet quality scores in the highest quintile had lower levels of disability (PDDS; proportional odds ratio [OR] for Q5 vs Q1 0.80; 95% confidence interval [CI] 0.69–0.93) and lower depression scores (proportional OR for Q5 vs Q1 0.82; 95% CI 0.70–0.97). Individuals reporting a composite healthy lifestyle had lower odds of reporting severe fatigue (0.69; 95% CI 0.59–0.81), depression (0.53; 95% CI 0.43–0.66), pain (0.56; 95% CI 0.48–0.67), or cognitive impairment (0.67; 95% CI 0.55–0.79).

[B]Conclusions[/B] Our large cross-sectional survey suggests a healthy diet and a composite healthy lifestyle are associated with lesser disability and symptom burden in MS.[/QUOTE]
Marsei

OMS over dit onderzoek

Bericht door Marsei »

OMS over dit onderzoek

[URL="https://overcomingms.org/last-high-leve ... isability/"][U]OMS[/U][/URL] over dit onderzoek:
[QUOTE]Anyone following the OMS Recovery Program will tell you of their frustration that, despite all the evidence pointing strongly to a role for diet in preventing MS progression, healthcare workers continue to say there is insufficient evidence to recommend a dietary approach.

Well at last we have high level science! Led by researchers at Johns Hopkins and using the NARCOMS (North American Research Committee on Multiple Sclerosis) dataset, this study looked at the diets of nearly 7,000 people with MS from North America and assessed how the quality of the diet was associated with disability.

To do this they basically split the diet into four components:
(1) fruits, vegetables and legumes
(2) wholegrains
(3) refined sugar and
(4) red meat.

Individuals were scored into quintiles according to how healthy their diet was in each domain and the scores summed. Those people with MS in the highest quintile overall for healthiest diet (ie most fruit and vegetables, most wholegrains, least sugar, and least meat) were 20% less likely to be severely vs mildly disabled.

Even more importantly, from an OMS Program point of view, they combined that score with the few other markers of healthy lifestyle they had on smoking, exercise and body weight and found that those in the healthiest group overall had around one-third less fatigue, around a half the incidence of depression and pain, and around a third less cognitive impairment.

These findings are strikingly similar to those of the HOLISM study to date, although HOLISM has considerably more data on healthy lifestyle behaviours, allowing much more robust independent associations to be discovered.

An editorial by experts in the field noted that as far as diet and MS was concerned, science had finally taken a seat at the table. For people following the OMS Program, this is strong endorsement that we are on the right track. While we await further intervention trials to confirm these findings, people with MS should have no hesitation in embracing the OMS Program, backed as it is by a growing credible evidence base from high quality research.[/QUOTE]
Marsei

SALT INTAKE DOESN’T INFLUENCE MS RISK OR ITS PROGRESSION

Bericht door Marsei »

SALT INTAKE DOESN’T INFLUENCE MS RISK OR ITS PROGRESSION

[URL="https://overcomingms.org/salt-intake-do ... ogression/"][U]SALT INTAKE[/U][/URL] DOESN’T INFLUENCE MS RISK OR ITS PROGRESSION

[QUOTE]There has now been a decades-long search for modifiable lifestyle risk factors that might increase the risk of developing MS or the risk of it progressing after diagnosis. Strong data now exist for low vitamin D levels, lack of sun exposure, especially during winter in childhood, a high animal fat diet, lack of exercise, smoking, overweight and obesity, stress and omega 3 fatty acid intake. But recently the question of the risk of having too much salt in the diet has come to the fore, with studies suggesting a causative link. However, a large international collaboration of experienced MS researchers has now examined this issue in very sophisticated research that effectively puts the theory to bed.

Researchers including high profile MS epidemiologists Prof Alberto Ascherio and Dr Kassandra Munger in the neuroepidemiology group at Harvard School of Public Health with great experience in these large epidemiological and clinical studies, approached the question of risk of MS with increasing salt intake by examining associations in the very large and ongoing US Nurses Health Study. This study of the health of 175,000 nurses in the USA has already yielded powerful data on a variety of the risk factors for MS development. Using prospectively collected dietary data, they showed absolutely no association between risk of later development of MS and increasing salt intake. These data were controlled for other confounding lifestyle habits like smoking, vitamin D intake, body mass index and so on.

In a separate and very rigorous clinical trial, they looked at even stronger data on how much sodium people with clinically isolated syndrome (CIS) were excreting in their urine (a good measure of salt intake) and subsequent conversion to definite MS, and disease progression, using relapse rate, MRI measures and disability score. As we know, CIS is for most people an early form of MS, for which the risk of converting to definite MS can be influenced by a variety of lifestyle factors. Again, they found no relationship whatsoever between higher salt intake and likelihood of conversion to MS or disease progression on any of these measures.

Together, these studies put the salt hypothesis to bed. While excess salt intake is not encouraged for anyone, due to its effects particularly in causing high blood pressure, people with MS can be reassured that salt intake is not a risk factor for the illness progressing, nor for their family developing the disease.[/QUOTE]
Marsei

Vitamine C bevordert remyelinisatie van zenuwbanen

Bericht door Marsei »

Vitamine C bevordert remyelinisatie van zenuwbanen

[URL="https://www.vnig.nl/nieuws/vitamine-c-b ... enuwbanen/"][U]Vitamine C[/U][/URL] bevordert remyelinisatie van zenuwbanen

[QUOTE]In het medische tijdschrift Glia beschrijven onderzoekers van de Universiteit van Shanghai hun experiment met vitamine C (Guo, Suo, Cui, Yuan, & Xie, 2018). Vitamine C bleek in vivo de aanmaak van myeline te versterken.[/QUOTE]

[QUOTE]Gebleken is dat vitamine C de omzetting van bouwstoffen naar myeline enorm versnelt en in die zin is het ook actief bij herstelprocessen van beschadigde myelineschedes.

Bovendien verhinderde vitamine C de verdere afbraak van myeline. [/QUOTE]
Artemis-

Bericht door Artemis- »

Marsei, heb jij enig idee hoeveel vitamine C we (dagelijks) moeten suppleren om een zodanig hoog level C en dus positief effect te verkrijgen m.b.t. herstel van myeline ?
Of zou dit eventueel met extra stuks fruit te behalen zijn?
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