Repetitive Transcranial Magnetic Stimulation is niet invasief, geen bijwerkingen.. Zelfs in Bulgarije gaan mensen vooruit en hier bleven we bij de oude, vertrouwde medicatie die in 30% van de patiënten effect heeft...
Spijtig...
"...Dr. Violeta Kateva bediende rTCS apparaat, waarbij 90% van de MS-patiënten na de 4e tot 6e procedure had verbetering bij de spasticiteit van de onderste ledematen, verbetering in de coördinatie, verbetering bij lopen, toegenomen kracht in de benen, beter slapen en betere stemming...."
[URL="http://forummedicus.com/archives/all-publications/4304"]Hier[/URL] is de bron, je kan de tekst via Google translate vertalen
rTMS helpt bij 90% patienten
-
Marsei
The use of rTMS for the treatment of spasticity (2009)
The use of rTMS for the treatment of spasticity (2009)
The use of [URL="https://www.ncbi.nlm.nih.gov/pubmed/19660671"][U]repetitive transcranial magnetic stimulation (rTMS)[/U][/URL] for the treatment of spasticity
[QUOTE][B]Abstract[/B]
Spasticity is a common disorder in patients with injury of the brain and spinal cord, especially in patients affected by multiple sclerosis (MS). In MS, spasticity is a major cause of long-term disability, it significantly impacts daily activities and quality of life and is only partially influenced by traditional spasmolytic drugs. Transcranial magnetic stimulation (TMS) is a noninvasive tool that can be used to modulate cortical excitability of the leg motor area, inducing remote effects on the excitability of the spinal circuits. The H reflex is a reliable electrophysiologic measure of the stretch reflex, and has been used in previous studies to test the effects of rTMS of the motor cortex on spinal circuitry. Based on these premises, originating from physiological studies in normal subjects, some studies have demonstrated that rTMS of the leg motor cortex can be beneficial in the management of spasticity by enhancing corticospinal tract excitability and reducing H reflex amplitude.
[/QUOTE]
The use of [URL="https://www.ncbi.nlm.nih.gov/pubmed/19660671"][U]repetitive transcranial magnetic stimulation (rTMS)[/U][/URL] for the treatment of spasticity
[QUOTE][B]Abstract[/B]
Spasticity is a common disorder in patients with injury of the brain and spinal cord, especially in patients affected by multiple sclerosis (MS). In MS, spasticity is a major cause of long-term disability, it significantly impacts daily activities and quality of life and is only partially influenced by traditional spasmolytic drugs. Transcranial magnetic stimulation (TMS) is a noninvasive tool that can be used to modulate cortical excitability of the leg motor area, inducing remote effects on the excitability of the spinal circuits. The H reflex is a reliable electrophysiologic measure of the stretch reflex, and has been used in previous studies to test the effects of rTMS of the motor cortex on spinal circuitry. Based on these premises, originating from physiological studies in normal subjects, some studies have demonstrated that rTMS of the leg motor cortex can be beneficial in the management of spasticity by enhancing corticospinal tract excitability and reducing H reflex amplitude.
[/QUOTE]
-
Marsei
Duitse trial
Duitse trial
Repetitive Deep Transcranial Magnetic Stimulation in Multiple Sclerosis [URL="https][U](rTMS in MS[/U][/URL])
[QUOTE][B]Primary Outcome Measures[/B]:
Safety [ Time Frame] [ Designated as safety issue]
examination by physician, assessement of adverse events
[B]Secondary Outcome Measures[/B]:
Fatigue [ Time Frame] [ Designated as safety issue]
Assessment of Fatigue via Fatigue Severity Scale FSS
[B]Depressivity[/B] [ Time Frame] [ Designated as safety issue]
Assessment of Depressivity via Beck Depression Inventory BDI
[/QUOTE]
Repetitive Deep Transcranial Magnetic Stimulation in Multiple Sclerosis [URL="https][U](rTMS in MS[/U][/URL])
[QUOTE][B]Primary Outcome Measures[/B]:
Safety [ Time Frame] [ Designated as safety issue]
examination by physician, assessement of adverse events
[B]Secondary Outcome Measures[/B]:
Fatigue [ Time Frame] [ Designated as safety issue]
Assessment of Fatigue via Fatigue Severity Scale FSS
[B]Depressivity[/B] [ Time Frame] [ Designated as safety issue]
Assessment of Depressivity via Beck Depression Inventory BDI
[/QUOTE]
-
Bixi
-
MiSsty
-
Bixi
[QUOTE]Abstract
Introduction: We studied the effect and safety of 10 day treatment with high frequency (15 Hz) repetitive transcranial magnetic stimulation (rTMS) applied bilaterally over the primary motor cortex in patients with multiple sclerosis (MS) in clinical settings. We investigated a heterogeneous group of 35 patients with MS—31 with spasticity, 32 with decreased muscle strength, 14 with mood disturbances, 23 with bladder control impairment, 11 with bowel control impairment and 13 with fatigue. Methods: We used the Modified Ashworth Spasticity Scale; the five point scale for muscle strength; Timed 25 foot walk test; Beck's Depression Inventory; Bladder and Bowel Control Scales from the Multiple Sclerosis Quality of Life Inventory and Fatigue Severity Scale. The patients were evaluated on the first and on the last day of treatment. For statistical comparison of the results before and after treatment we used Wilcoxon Signed Rank Test. Results: All the symptoms, excluding fatigue, were significantly improved. Twenty four patients did the Timed 25 Foot Walk Test and 16 (67%) had clinically significant improvement. None of the patients had any serious adverse events. Conclusions: Repetitive TMS is beneficial in the management of motor, affective, bladder and bowel symptoms in patients with MS. The procedure has excellent safety profile.[/QUOTE]
[URL="https://www.researchgate.net/publicatio ... _Sclerosis"]bron[/URL]
Ik heb wel via Google klinieken in Nederland gevonden die rTMS succesvol toepassen bij de depressie..
Introduction: We studied the effect and safety of 10 day treatment with high frequency (15 Hz) repetitive transcranial magnetic stimulation (rTMS) applied bilaterally over the primary motor cortex in patients with multiple sclerosis (MS) in clinical settings. We investigated a heterogeneous group of 35 patients with MS—31 with spasticity, 32 with decreased muscle strength, 14 with mood disturbances, 23 with bladder control impairment, 11 with bowel control impairment and 13 with fatigue. Methods: We used the Modified Ashworth Spasticity Scale; the five point scale for muscle strength; Timed 25 foot walk test; Beck's Depression Inventory; Bladder and Bowel Control Scales from the Multiple Sclerosis Quality of Life Inventory and Fatigue Severity Scale. The patients were evaluated on the first and on the last day of treatment. For statistical comparison of the results before and after treatment we used Wilcoxon Signed Rank Test. Results: All the symptoms, excluding fatigue, were significantly improved. Twenty four patients did the Timed 25 Foot Walk Test and 16 (67%) had clinically significant improvement. None of the patients had any serious adverse events. Conclusions: Repetitive TMS is beneficial in the management of motor, affective, bladder and bowel symptoms in patients with MS. The procedure has excellent safety profile.[/QUOTE]
[URL="https://www.researchgate.net/publicatio ... _Sclerosis"]bron[/URL]
Ik heb wel via Google klinieken in Nederland gevonden die rTMS succesvol toepassen bij de depressie..
-
MiSsty
-
Bixi
Hoi,
Het is Bulgaars en ja, ik overweeg serieus, eigenlijk is het nog kwestie van organisatie om daarnaartoe te gaan. Ik vind het meest belovend met bijna altijd positieve resultaten, minst ingrijpend en zonder gevaren en negatieve impact..
Vraag is na hoeveel sessies (in combinatie met de fysiotherapie en zelf actief oefene zoals het in rev.centrum gedan wordt) gaat verbetering optreden zoals ik het gehoord heb.
Wat mij betreft is het meer dan genoeg overtuigend...
Het is Bulgaars en ja, ik overweeg serieus, eigenlijk is het nog kwestie van organisatie om daarnaartoe te gaan. Ik vind het meest belovend met bijna altijd positieve resultaten, minst ingrijpend en zonder gevaren en negatieve impact..
Vraag is na hoeveel sessies (in combinatie met de fysiotherapie en zelf actief oefene zoals het in rev.centrum gedan wordt) gaat verbetering optreden zoals ik het gehoord heb.
Wat mij betreft is het meer dan genoeg overtuigend...
-
Bixi
[QUOTE]Results: Our study showed that (5Hz) rTMS increased H/M amplitude ratio with significant improvement of the lower limb spasticity scales, while the (1Hz) rTMS sessions showed no improvement of H/M ratio as well as the spasticity scales. Conclusion: (5Hz) rTMS can contribute in improving the MS spasticity and hence improving quality of patients' life.[/QUOTE]
[URL="https://www.researchgate.net/publicatio ... tian_Study"]Bron[/URL]
[URL="https://www.researchgate.net/publicatio ... tian_Study"]Bron[/URL]