Per 1 februari is dit forum niet meer actief. Je account en bijbehorende gegevens op dit forum zijn daarom verwijderd. Oude berichten kun je nog wel nalezen. We zien je eind februari graag terug in de nieuwe community van MS.nl. Meer informatie lees je op MS.nl of in dit topic.

Secundair Progressieve Multiple Sclerose

Alles omtrent voeding en supplementen
Marsei

Secundair Progressieve Multiple Sclerose

Bericht door Marsei »

Multiple sclerosis: [URL="http://www.medicalnewstoday.com/articles/318225.php"][U]Antioxidant[/U][/URL] may slow disease progression - Onderzoek naar Lipoic acid

[QUOTE]In a pilot study, researchers found that taking a high dose of lipoic acid every day for 2 years reduced whole brain atrophy among patients with secondary progressive multiple sclerosis (SPMS), compared with a placebo.[/QUOTE]
[QUOTE]Dr. Spain and colleagues suggest that lipoic acid - a naturally occurring antioxidant that is available as an over-the-counter supplement - could be an effective treatment for SPMS, after finding that it helped to reduce the rate of whole brain atrophy among patients with the condition.

[B]Lipoic acid outperformed ocrelizumab
[/B]
Whole brain atrophy refers to the reduction in total brain volume due to the loss of neurons, and it is considered a marker of MS progression.

For their randomized, double-blind study, Dr. Spain and team enrolled 51 adults aged between 40 and 70 years, all of whom had been diagnosed with SPMS.

A total of 27 participants were randomized to receive 1,200 milligrams of lipoic acid every day for 2 years, while the remaining 24 subjects received a placebo.

The brain volume of each participant was assessed at study baseline using MRI. MRI scans were also conducted each year thereafter, in order to pinpoint any changes in subjects' brain volume.

[B]Compared with participants who took the placebo, the researchers found that those who took lipoic acid showed a 68 percent reduction in the rate of whole brain atrophy.[/B]

For comparative purposes, the team notes that the drug ocrelizumab (brand name Ocrevus) - which was recently approved by the Food and Drug Administration (FDA) for the treatment of primary progressive MS - improved whole brain atrophy by 18 percent in clinical trials.

What is more, the new study revealed that participants treated with lipoic acid experienced fewer falls and better walking times, compared with subjects who received the placebo.

Importantly, the researchers found that lipoic acid was generally safe and well tolerated by participants, with the most common side effect being gastrointestinal upset.

However, the team cautions that further trials in a larger number of patients are needed before lipoic acid can be recommended as a safe and effective treatment for MS.

"These are high doses. And while it seems safe, we won't know whether it actually improves the lives of people with MS until we can replicate the results in the pilot study through a much bigger clinical trial."
Dr. Rebecca Spain

"Fortunately, we're going to be able to answer that question with the participation of kind volunteers," adds Dr. Spain.

Using the results of their pilot study, the researchers are currently designing a multisite clinical trial that is due to start later this year.
[/QUOTE]
Bixi

Bericht door Bixi »

Super Marsei, bedankt!
Jantien

Lipoic acid

Bericht door Jantien »

Lipoic acid

Vraagje:

Is Lipoic acid hetzelfde als Alfa Liponzuur?
Klick

Bericht door Klick »

dan zou dit dus voor 30 dagen zijn
[url]https://www.bodyenfitshop.nl/andere-pro ... cid-600mg/[/url]

kun je dit spul eigenlijk ongestraft nemen? of kan het ook nadelen hebben? wat weten we ervan?

ik ben nog niet sp, maar lees ook niet dat het bij rr geen positief effect zou hebben..
Klick

Bericht door Klick »

het middel is eerder besproken:

[url]https://www.msweb.nl/forum/showthread.php?t=23509[/url]
Plaats reactie Vorig onderwerpVolgend onderwerp