Sir 2013 agenda incompleet
[url]http://www.sirmeeting.org/index.cfm?do= ... ay=all:huh:[/url]
CCSVI - 9
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Marsei
Italiaanse onderzoeksresultaten
Italiaanse onderzoeksresultaten
[URL="http://www.minervamedica.it/en/journals ... 12N03A0141"][U]Results[/U][/URL] from 823 consecutive Duplex exams for CCSVI in a Vascular Centre
[QUOTE][B]Aim[/B]. Ultrasound (US) diagnosis of chronic cerebrospinal venous insufficiency (CCSVI) and its association with MS is highly controversial, perhaps for lack of both training and awareness of what is normal in cervical veins mainly because they are not segments usually investigated in Vascular Labs.
[B]Methods[/B]. The work is based upon the results of 823 consecutive Duplex (DU) exams carried out in one year on Multiple Sclerosis (MS) patients. The purpose was to eventually detect and quantify the presence of CCSVI and possible benefits on PTA-treated patients, according to the Zamboni criteria protocol. The authors scanned first a consecutive group of 60 controls, not affected by MS, aged 28-62 years old, in order to improve the personal learning curve in investigating the cervical veins. Therefore they investigated 696 MS patients and 127 MS patients post-PTA treatment for diagnosed CCSVI.
[B]Results[/B]. Within the 60 controls, only 3 (5%) showed one flow abnormality according to the Zamboni criteria, considered insufficient for CCSVI diagnosis, while in the remaining 57 (95%) they were totally absent. In the 823 patients affected by MS, 627 (90%) matched with sufficient Zamboni criteria scores. The frequency of CCSVI among MS patients and non-MS controls revealed a higher CCSVI prevalence in the MS group (odds ratio 576.7; 95% confidence interval 286.2-1161.9; χ2=310 and P-value<0.0001). Finally, 88 patients (69%) of the post procedural Duplex examination were negative for CCSVI Zamboni criteria and this result was associated to symptoms improvements. Other previous, but smaller studies, were previously carried out with the aim to investigate CCSVI in MS and the lack of detection in this particular population of patients may be subsequent to insufficient training and completion of an adequate learning curve.
[B]Conclusion[/B]. The present study demonstrates in a large survey, the strong association between the two conditions. In addition, PTA may revert abnormal duplex haemodynamics in a large proportion of patients.[/QUOTE]
[URL="http://www.minervamedica.it/en/journals ... 12N03A0141"][U]Results[/U][/URL] from 823 consecutive Duplex exams for CCSVI in a Vascular Centre
[QUOTE][B]Aim[/B]. Ultrasound (US) diagnosis of chronic cerebrospinal venous insufficiency (CCSVI) and its association with MS is highly controversial, perhaps for lack of both training and awareness of what is normal in cervical veins mainly because they are not segments usually investigated in Vascular Labs.
[B]Methods[/B]. The work is based upon the results of 823 consecutive Duplex (DU) exams carried out in one year on Multiple Sclerosis (MS) patients. The purpose was to eventually detect and quantify the presence of CCSVI and possible benefits on PTA-treated patients, according to the Zamboni criteria protocol. The authors scanned first a consecutive group of 60 controls, not affected by MS, aged 28-62 years old, in order to improve the personal learning curve in investigating the cervical veins. Therefore they investigated 696 MS patients and 127 MS patients post-PTA treatment for diagnosed CCSVI.
[B]Results[/B]. Within the 60 controls, only 3 (5%) showed one flow abnormality according to the Zamboni criteria, considered insufficient for CCSVI diagnosis, while in the remaining 57 (95%) they were totally absent. In the 823 patients affected by MS, 627 (90%) matched with sufficient Zamboni criteria scores. The frequency of CCSVI among MS patients and non-MS controls revealed a higher CCSVI prevalence in the MS group (odds ratio 576.7; 95% confidence interval 286.2-1161.9; χ2=310 and P-value<0.0001). Finally, 88 patients (69%) of the post procedural Duplex examination were negative for CCSVI Zamboni criteria and this result was associated to symptoms improvements. Other previous, but smaller studies, were previously carried out with the aim to investigate CCSVI in MS and the lack of detection in this particular population of patients may be subsequent to insufficient training and completion of an adequate learning curve.
[B]Conclusion[/B]. The present study demonstrates in a large survey, the strong association between the two conditions. In addition, PTA may revert abnormal duplex haemodynamics in a large proportion of patients.[/QUOTE]
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Marsei
Harald U. Sverdrup speciale gastspreker bij ISNVD symposium in Polen
Harald U. Sverdrup speciale gastspreker bij ISNVD symposium in Polen
Van FB:
[QUOTE]I have received notification from Dr Simka, President of ISNVD, that Harald U. Sverdrup has been added to the program in Krakow as his "special guest" speaker. Harald will be presenting his groups sophisticated systems analysis of MS and CCSVI research data. Dr Simka has given him an amazing 30 minutes, which is an indication of the importance of this work. Their book is being published very soon by the University of Lund in Sweden. Kudos Professor Sverdrup![/QUOTE]
Van FB:
[QUOTE]I have received notification from Dr Simka, President of ISNVD, that Harald U. Sverdrup has been added to the program in Krakow as his "special guest" speaker. Harald will be presenting his groups sophisticated systems analysis of MS and CCSVI research data. Dr Simka has given him an amazing 30 minutes, which is an indication of the importance of this work. Their book is being published very soon by the University of Lund in Sweden. Kudos Professor Sverdrup![/QUOTE]
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joge
Interessant. Wat doceert hij? [url]http://www.ncbi.nlm.nih.gov/pubmed?term ... 20sverdrup[/url] Als ik zo kijk gaat het niet over geneeskunde. Of heb ik hier de verkeerde te pakken? Ik denk 't niet. Dat maakt me alleen maar nieuwsgieriger! [url]http://www2.chemeng.lth.se/staff/harald/[/url]
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Marsei
[QUOTE=joge;894931][url]http://www2.chemeng.lth.se/staff/harald/[/url][/QUOTE]
Zal wel dezelfde zijn, beide systeem-analyse.
Zal wel dezelfde zijn, beide systeem-analyse.
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Marsei
COSMO study--Vascular Specialists offer a Re-Do
COSMO study--Vascular Specialists offer a Re-Do
Van [URL="https://www.facebook.com/notes/ccsvi-in ... 3140712211"][U]FB[/U][/URL]: COSMO study--Vascular Specialists offer a Re-Do
[QUOTE]The Vascular Specialists in the Lombardi region of Italy are repeating the "blinded" CCSVI COSMO doppler study---this time with trained vascular professionals.
[URL="http://it.paperblog.com/sclerosi-multip ... u-1596046/"][U]link[/U][/URL] to Italian article
Here are the reasons these vascular specialists are repeating the test:
1. The COSMO study results were modified by three central readers, who threw out 90% of the positive CCSVI results in pwMS.
[URL="https://www.facebook.com/notes/ccsvi-in ... 6647652211"][U]link[/U][/URL]
2. The study coordinator, Giancarlo Comi, blatantly violated a feature of clinical trials, in that he came out announcing negative results at ECTRIMS 2011, when more than 75% of the patients had yet to be tested.
[URL="https://www.facebook.com/notes/ccsvi-in ... 6960927211"][U]link[/U][/URL]
3. The sonologists were not trained properly, which is why Dr. Zamboni stepped down from this trial in September 2010, when he saw that Comi would not comply with his doppler protocol training requirements.
The Lombardi region Vascular Specialists believe the only way to correct this travesty is to have ALL participants blindly retested.
The have included a standard form at the above Italian link, so that each person who was tested can fill it in and return to [email]info@ccsvi-lombardia.org[/email]
Please share this with your CCSVI community--and know that those of us who want UNBIASED, INDEPENDENT research, without pharmaceutical involvement, must fight for honesty and transparency.[/QUOTE]
Van [URL="https://www.facebook.com/notes/ccsvi-in ... 3140712211"][U]FB[/U][/URL]: COSMO study--Vascular Specialists offer a Re-Do
[QUOTE]The Vascular Specialists in the Lombardi region of Italy are repeating the "blinded" CCSVI COSMO doppler study---this time with trained vascular professionals.
[URL="http://it.paperblog.com/sclerosi-multip ... u-1596046/"][U]link[/U][/URL] to Italian article
Here are the reasons these vascular specialists are repeating the test:
1. The COSMO study results were modified by three central readers, who threw out 90% of the positive CCSVI results in pwMS.
[URL="https://www.facebook.com/notes/ccsvi-in ... 6647652211"][U]link[/U][/URL]
2. The study coordinator, Giancarlo Comi, blatantly violated a feature of clinical trials, in that he came out announcing negative results at ECTRIMS 2011, when more than 75% of the patients had yet to be tested.
[URL="https://www.facebook.com/notes/ccsvi-in ... 6960927211"][U]link[/U][/URL]
3. The sonologists were not trained properly, which is why Dr. Zamboni stepped down from this trial in September 2010, when he saw that Comi would not comply with his doppler protocol training requirements.
The Lombardi region Vascular Specialists believe the only way to correct this travesty is to have ALL participants blindly retested.
The have included a standard form at the above Italian link, so that each person who was tested can fill it in and return to [email]info@ccsvi-lombardia.org[/email]
Please share this with your CCSVI community--and know that those of us who want UNBIASED, INDEPENDENT research, without pharmaceutical involvement, must fight for honesty and transparency.[/QUOTE]
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Marsei
Synergy heeft meer dan 2000 CCSVI behandelingen uitgevoerd
Synergy heeft meer dan 2000 CCSVI behandelingen uitgevoerd
Van Dr Arata op Twitter:
[QUOTE]As of January 2013 Synergy has performed the CCSVI procedure over 2000 times.[/QUOTE]
Van Dr Arata op Twitter:
[QUOTE]As of January 2013 Synergy has performed the CCSVI procedure over 2000 times.[/QUOTE]
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TvG
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joge