MS Progression Time Predicts Disability
MS Progression Time Predicts Disability
[URL="http://www.medpagetoday.com/clinical-co ... osis/36012"][U]MS Progression[/U][/URL] Time Predicts Disability
[QUOTE]Time to secondary progression in multiple sclerosis (MS), not the frequency of early inflammatory attacks, was the strongest predictor of severe disability later on, researchers found.[/QUOTE]
[QUOTE]"We provide strong evidence that relapse frequency cannot be validated as a surrogate marker for late disability accumulation, questioning the current practice of using relapse rate as the primary endpoint in trials," they stated.[/QUOTE]
[QUOTE]Time to secondary progression in multiple sclerosis (MS), not the frequency of early inflammatory attacks, was the strongest predictor of severe disability later on, researchers found.[/QUOTE]
[QUOTE]"We provide strong evidence that relapse frequency cannot be validated as a surrogate marker for late disability accumulation, questioning the current practice of using relapse rate as the primary endpoint in trials," they stated.[/QUOTE]
[QUOTE=Marsei;881787][URL="http://www.medpagetoday.com/clinical-co ... osis/36012"][U]MS Progression[/U][/URL] Time Predicts Disability[/QUOTE]
Kortom omdat we de oorzaak van de ziekte niet weten hebben we nu tenminste 30 jaar (en heel erg veel geld) verspeeld met het voorschrijven van (genees)middelen die niet werken.
Kortom omdat we de oorzaak van de ziekte niet weten hebben we nu tenminste 30 jaar (en heel erg veel geld) verspeeld met het voorschrijven van (genees)middelen die niet werken.
Ja, er is nog een langlopend onderzoek geweest (15 jaar dacht ik) dat uitwees dat de huidige middelen wel het aantal schubs (wat) verminderde maar dat de beschadiging gewoon doorgaat...
[url]http://www.newsmaxhealth.com/health_sto ... 62806.html[/url]
[url]http://www.newsmaxhealth.com/health_sto ... 62806.html[/url]
[QUOTE=Marsei;881787][URL="http://www.medpagetoday.com/clinical-co ... osis/36012"][U]MS Progression[/U][/URL] Time Predicts Disability[/QUOTE]
maar natuurlijk, de uitleg staat hier :)
[url]http://www.thisisms.com/forum/general-d ... 15188.html[/url]
maar natuurlijk, de uitleg staat hier :)
[url]http://www.thisisms.com/forum/general-d ... 15188.html[/url]
Medicatie houdt schubs tegen, maar niet de achteruitgang/progressie.
Zie:
[url]http://www.msweb.nl/therapeutisch/3888[/url]
Zie:
[url]http://www.msweb.nl/therapeutisch/3888[/url]
[QUOTE=Vlinder70;881847]Medicatie houdt schubs tegen, maar niet de achteruitgang/progressie.
Zie:
[url]http://www.msweb.nl/therapeutisch/3888[/url][/QUOTE]
Twaalfjaar geleden is dat ook al eens gepubliceerd.
[url]http://multiple-sclerosis-research.blog ... s-not.html[/url]
Zie:
[url]http://www.msweb.nl/therapeutisch/3888[/url][/QUOTE]
Twaalfjaar geleden is dat ook al eens gepubliceerd.
[url]http://multiple-sclerosis-research.blog ... s-not.html[/url]
Early Disease Activity in MS Seen to Have Little Long-Term, Prognostic Value
Early Disease Activity in MS Seen to Have Little Long-Term, Prognostic Value
Early Disease Activity in MS Seen to Have [URL="https://multiplesclerosisnewstoday.com/ ... stic+Value+"][U]Little Long-Term, Prognostic Value[/U][/URL]
[QUOTE]A large study of multiple sclerosis patients (MS) came to the conclusion that clinical and brain imaging assessments drawn from magnetic resonance imaging (MRI) scans are poor measures of long-term prognosis for patients.[/QUOTE]
[QUOTE]The study, “Long-term evolution of multiple sclerosis disability in the treatment era,” published in the journal Annals of Neurology, also showed that a lack of disease activity in the immediate years following disease onset does not predict later outcomes, and questions the use of yearly MRI assessments and whether aggressive early treatment to halt disease activity can actually ensure lower disability over time.[/QUOTE]
[QUOTE]Long-term outcomes also did not differ between patients who, at some time point during the first two years, intensified their treatment compared to those who did not.[/QUOTE]
Early Disease Activity in MS Seen to Have [URL="https://multiplesclerosisnewstoday.com/ ... stic+Value+"][U]Little Long-Term, Prognostic Value[/U][/URL]
[QUOTE]A large study of multiple sclerosis patients (MS) came to the conclusion that clinical and brain imaging assessments drawn from magnetic resonance imaging (MRI) scans are poor measures of long-term prognosis for patients.[/QUOTE]
[QUOTE]The study, “Long-term evolution of multiple sclerosis disability in the treatment era,” published in the journal Annals of Neurology, also showed that a lack of disease activity in the immediate years following disease onset does not predict later outcomes, and questions the use of yearly MRI assessments and whether aggressive early treatment to halt disease activity can actually ensure lower disability over time.[/QUOTE]
[QUOTE]Long-term outcomes also did not differ between patients who, at some time point during the first two years, intensified their treatment compared to those who did not.[/QUOTE]