BCG vaccin

[Marsei]

[URL="http://www.wheelchairkamikaze.com/2018/ ... l?spref=fb"][U]Wheelchair Kamikaze[/U][/URL]: Can A 100-Year-Old TB Vaccine Stop MS, Diabetes, and Other Diseases?

[QUOTE]Other studies have shown that BCG can alter the course and severity of multiple sclerosis, and ongoing studies around the world indicate that the vaccine could have similar effects on a wide range of autoimmune diseases, including Sjogren’s disease, fibromyalgia, and immune mediated allergies. [/QUOTE]
[QUOTE]Italian researchers, using the same multiple BCG vaccination approach and the same potent strain of BCG, have demonstrated that patients given the vaccine after their first MS attack are up to 50% less likely to develop full-blown multiple sclerosis than similar patients not given BCG (click here), and that those who are eventually diagnosed with multiple sclerosis experience a more benign disease course. Click on the graphic to the left for a visual representation of BCG's effects on MS. Further studies are expected to explore whether aggressive treatment with BCG may temper or stop already established MS.[/QUOTE]
[QUOTE]Unfortunately, a variety of factors are hampering research into the benefits of BCG. Modern studies exploring the use of the vaccine to combat autoimmune and other diseases are still in their early stages, and many questions remain. The vaccine is manufactured using live but inactive bacteria, meaning its potency varies depending on the manufacturing facility.[/QUOTE]
[QUOTE]The most significant impediment to the development of BCG as a therapy for autoimmune and other diseases, though, is a severe lack of funding. Since the drug is nearly a century old and quite cheap (single doses cost pennies in Third World nations) there is very little to incentivize the for-profit medical establishment to get behind the research. The reasons for this are myriad, but boil down to the obscene fact that all too often profits take precedence over patients in our current twisted model of medical research, which is more often propelled by the drive for ever-increasing revenues than by scientific imperative. Many potentially paradigm-shifting therapies like BCG have been left to die on the vine simply because they lack blockbuster profit potential. MS and diabetes have become mega industries generating yearly revenues of $25 billion each, creating a status quo that discourages disruptive innovation. We can’t kill the geese that lay the golden eggs, now, can we?

Research into the BCG vaccine holds tremendous possibilities for fundamentally changing the treatment landscape for a wide variety of terrible diseases that are being seen with dramatically increasing frequency, including multiple sclerosis. In a perfect world, or even a less imperfect one, massive resources would be devoted to investigating BCG and other treatments that hold great promise but little profit potential. Instead, innovative researchers like Dr. Faustman and her colleagues are left to work in the shadows while a seemingly never-ending stream of “me too” drugs are brought to market, fueling massive industries devoted to treating diseases, not curing them. [/QUOTE]
[QUOTE][URL="https://www.youtube.com/watch?v=BMmO2MWECv0"][U]Video[/U][/URL]: Denise Faustman MD, PhD “The Value of Advanced BCG Drug Development in Human Autoimmunity; Mechanistic Biomarkers for Trial Design; Vaccine for Type 1 Diabetes” presented at The Powering Precision Health Summit 2017[/QUOTE]